Registered Nurse Salary vs. Physician Assistant Salary: Full Breakdown
Both roles are licensed, both are growing, and the pay difference traces back to how long each takes to train for and who signs the paycheck.

Registered nurses and physician assistants both deliver hands-on patient care, but they are paid on different structures: RNs are commonly hourly with shift differentials and overtime, while PAs are more often salaried with call or productivity pay on top. The U.S. Bureau of Labor Statistics publishes a median annual wage for each occupation for May 2025 (BLS, 2025), and those two figures side by side on the BLS Occupational Outlook Handbook pages are the cleanest head-to-head comparison available.
The bigger difference is the cost of entry. A PA needs a master's degree from an accredited program and a license in all 50 states and the District of Columbia (BLS, undated). An RN can be licensed after any one of three education routes (BLS, undated), which changes how fast you start earning.
Pay Side by Side
Both jobs are measured in the same BLS wage survey, so pull the matching figure for each from the same source and year rather than mixing a salary-site estimate for one with a government figure for the other.
| Comparison point | Registered nurse | Physician assistant |
|---|---|---|
| Entry-level pay | Lowest-10-percent annual wage, BLS registered nurses page, May 2025 (BLS, 2025); new graduates start near this end, hourly, plus shift differentials | Lowest-10-percent annual wage, BLS physician assistants page, May 2025 (BLS, 2025); new PA-C holders start near this end, usually salaried |
| Median pay | Median annual wage for registered nurses, May 2025 (BLS, 2025) | Median annual wage for physician assistants, May 2025 (BLS, 2025) |
| Senior / top pay | Highest-10-percent annual wage, same BLS page, May 2025 (BLS, 2025); reached by directors of nursing and chief nursing officers (BLS, undated) | Highest-10-percent annual wage, same BLS page, May 2025 (BLS, 2025); reached in surgical and specialty practice, including postgraduate-trained PAs (BLS, undated) |
| Typical path to top pay | Staff nurse, then experience and continuing education into assistant director, director of nursing or chief nursing officer (BLS, undated) | Pass the qualifying exam for PA-C, maintain it with continuing education and a recertification exam (BLS, undated), then specialise (BLS, undated) |
On each page, note three things: the median annual wage, the percentile spread, and the wage table by industry. The industry table is where most of the difference between two people holding the same credential shows up — hospital, outpatient clinic, nursing home and government employers do not pay the same rate.
For state figures, use the BLS state and metropolitan wage tables for each occupation, or CareerOneStop, which both BLS occupation pages point readers to for state licensing information (BLS, undated).
Why the Gap Exists
Start with the entry requirement. A physician assistant needs a master's degree from an accredited program, built on a bachelor's degree with science coursework and often prior patient-care experience as a medical assistant, EMT or paramedic (BLS, undated), followed by postbaccalaureate study covering classroom, laboratory and supervised clinical training (BLS, undated). A registered nurse has three routes: a bachelor's in nursing, an associate's in nursing, or a hospital diploma program (BLS, undated). Three doors in versus one is the most concrete structural reason the two wage distributions differ — a faster-filling supply pipeline sits behind the RN wage, a graduate-degree bottleneck behind the PA wage.
Scope of practice is the second factor. In most states PAs must hold an agreement with a supervising physician, though that physician need not be onsite at all times (BLS, undated). That arrangement lets a practice bill for PA-delivered visits, tying PA pay to revenue in a way staff nursing pay usually is not. RN pay is tied more to hours staffed, which is why night, weekend and holiday differentials plus overtime make up a real share of many nurses' annual earnings.
Employer type matters next. Hospitals employ RNs in large numbers, and in some states a substantial share of hospital nurses are covered by collective bargaining agreements with step scales, where raises follow years of service. PAs are more often hired by smaller units — a surgical group, a clinic, an emergency department — where pay is negotiated individually and may include call pay. PA pay is therefore more variable between two people in the same city; RN pay is more predictable within one employer.
Demand pulls both upward. BLS projects registered nurse employment to grow faster than the average for all occupations from 2025 to 2035, and physician assistant employment to grow much faster than average over the same decade (BLS, 2025), with large annual openings in each driven partly by workers transferring or leaving the labor force (BLS, 2025).
Which One Fits Your Priorities
- Fastest entry pay: registered nurse. You can be licensed through an associate's degree or a hospital diploma program and begin earning in the lowest-10-percent-to-median band on the BLS registered nurses page, May 2025 (BLS, 2025), while a PA candidate is still completing a bachelor's plus a master's program (BLS, undated).
- Highest reported ceiling: compare the two top-end numbers directly. Put the highest-10-percent annual wage for physician assistants next to the highest-10-percent annual wage for registered nurses, both May 2025 BLS data (BLS, 2025). The PA top end sits in specialty and surgical practice (BLS, undated); the RN top end sits in titles such as director of nursing and chief nursing officer (BLS, undated).
- Most stable raises: registered nurse in a unionised hospital system. Step scales move pay by years of service, while PA increases in a small practice are negotiated case by case; check the RN wage table by industry, May 2025 (BLS, 2025).
- Best pay in a specific state: use state data, not the national median. Pull state annual wages for both occupations from the BLS state tables, May 2025 (BLS, 2025); comparing California, Texas and Mississippi for the same credential often shows a wider spread than the national RN-versus-PA gap, driven by cost of living and local employer mix.
- Most room to specialise for pay: physician assistant. Postgraduate programs in fields such as emergency medicine and psychiatry require an accredited-program degree and the PA-C credential (BLS, undated); for RNs, association certification is usually voluntary, though some employers require it (BLS, undated).
Frequently asked questions
Does a physician assistant always out-earn a registered nurse?
Not in every case. The May 2025 median annual wage for physician assistants and the May 2025 median annual wage for registered nurses (BLS, 2025) are national midpoints only. A nurse in the upper percentiles of the RN annual wage distribution, working nights and overtime in a high-wage state, can land above a PA in the lower percentiles of the PA distribution in a low-wage state. Check the percentile spread and state tables for both.
Which job gets me earning sooner?
The RN route, because licensure follows an associate's degree, a hospital diploma program or a bachelor's degree plus a qualifying exam (BLS, undated), while PA licensure requires a master's degree first and is required in all 50 states and the District of Columbia (BLS, undated). Model both: RN earnings from the May 2025 entry-band figure for registered nurses against PA earnings starting later from the May 2025 entry-band figure for physician assistants (BLS, 2025).
Where do I find current pay for my own state?
Use the BLS state and metropolitan annual wage tables for registered nurses and for physician assistants, both from the May 2025 data release (BLS, 2025), so the two figures share a survey year. For the licensing behind those numbers, both BLS occupation pages point to CareerOneStop for state board requirements for RNs and PAs (BLS, undated).
Sources
- U.S. Bureau of Labor Statistics (BLS) — Registered Nurses : Occupational Outlook Handbook (2025)
- U.S. Bureau of Labor Statistics (BLS) — Physician Assistants : Occupational Outlook Handbook (2025)



